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The deposition of acylcarnitine also disrupts the function of the Na + -K + -ATP pump and affects the action potentials, polarization, hyperpolarization, and depolarization cycles of the myocardial cell membrane, which further affects the electrophysiological stability of the heart [295]
(2011) 159:8518.e1
By providing a comprehensive map of their effects, the recent study equips healthcare providers with the knowledge to make informed decisions, ensuring that these "miracle drugs" fulfill their promise while safeguarding patient well-being
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From a patient burden standpoint, people living with advanced CKD take a number of oral medications and may prefer a once-weekly injection to an additional daily oral medication
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